The Effects of Meperidine Analgesia during Labor on Fetal Heart Rate
نویسندگان
چکیده
To estimate the effects of intramuscular meperidine analgesia on fetal heart rate (FHR) patterns compared with placebo. In a prospective randomized study, 150 healthy women with singleton term pregnancy requesting analgesia during active labor were planned to receive either intramuscular meperidin 50 mg (meperidin group) or normal saline (control group) when they requested analgesia. Fetal heart rate patterns occurring within 40 minutes of initiation of labor analgesia were retrospectively read by maternal fetal medicine specialist who was blind to type of labor analgesia. Meperidine, compared with placebo, was associated with statistically significantly less beat to beat variability (absent or less than 5 beats per minute) (28% versus 5% of fetuses, P<0.05), lower proportion of accelerations (37.3% versus 17.3% P<0.05) and of the FHR. Also FHR deceleration was significantly more than control group (25.5% versus 4%, P<0.05). Meperidine has deleterious effects on FHR.
منابع مشابه
Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
BACKGROUND Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? METHOD 395 healthy, nulliparous women, at term, presented in spontan...
متن کاملThe Comparison of Patient-Controlled Remifentanil Administered by Two Different Protocols (Bolus and Bolus+Infusion) and Intramuscular Meperidine for Labor Analgesia.
OBJECTIVE Nowadays, there are many pain relief methods for reducing the pain and stress of labor and delivery. In our study, two different remifentanil protocols (bolus and bolus+infusion) administered by patient-controlled analgesia method were compared with intramuscular meperidine for labor analgesia. METHODS Ninety parturients who were scheduled for vaginal delivery were included in this ...
متن کاملمقایسه اثرات آرامبخشی پروپوفول- فنتانیل با میدازولام– مپریدین در بیماران تحت کولونوسکوپی انتخابی
Background and purpose: Colonoscopy is an invasive short-lasting procedure causes the patient's considerable pain, discomfort and anxiety. Therefore, various types of sedation and analgesia techniques have been used during the procedure. The aim of this study was to compare the quality of sedation/analgesia of propofol-fentanyl and midazolam-meperidine combinations in patients undergoing electi...
متن کاملComparison of effects of 5% Lidocaine and 5% Meperidine plus 5% Lidocaine on complications and duration of postoperative analgesia for cesarean section
Introduction: Nowadays, spinal anesthesia is associated with few complications in many surgical practices especially the elective caesarean which is taken as a suitable replacement for general anesthesia. Different drugs are used for spinal anesthesia. This study aims to compare lidocaine 5% in combination with meperidine 5% plus lidocaine 5% for spinal anesthesia in non-emergency cesarean pati...
متن کاملObstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour.
BACKGROUND To compare the analgesic efficacy of remifentanil with meperidine and fentanyl in a patient-controlled setting (patient-controlled analgesia, PCA). METHODS Parturients (n=159) were randomly assigned to receive remifentanil (n=52), meperidine (n=53), or fentanyl (n=54). Pain scores and an observer sedation scores were assessed hourly. Fetal outcome was evaluated with Apgar score, co...
متن کامل